Dead space mixing with fresh air lungs11/15/2023 ![]() ![]() Principal component analyses and multiple regression analyses were used to explore the relationships between subject characteristics and particle deposition. ![]() A comprehensive examination of lung function was performed for all subjects. The study covers particles of diameters 15–5000 nm and includes 67 subjects aged 7–70 years. In this study we experimentally investigate factors that determine individual differences in the respiratory tract depositions of inhaled particles for healthy subjects at relaxed breathing. The factors determining this variability are, however, not fully understood. ![]() Observations have shown that there is a substantial variability in deposition between subjects, not only due to respiratory diseases, but also among individuals with healthy lungs. The probability of these particles to deposit in the respiratory tract during breathing is essential for their toxic effects. Exposure to airborne particles has a major impact on global health. ![]()
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